From a social perspective, lockdowns are like trying to get humans to act out a reprise of the hunter-gatherer period, isolated in small groups and interacting infrequently. The failures of lockdowns are all related to the impossibility of really trying to live that way again.
The epidemiologists asked to advise governments almost invariably admitted that what they were advocating was only based on their projections of Covid cases and Covid deaths, devoid of any analysis of the effects these actions would have on public health, the economy, education and other important aspects of life. They nonetheless had no problem advocating lockdowns and other draconian measures.
Their singular obsession, emotional intensity, and size lead to crowds sometimes attaining great power and dictating directions that can change the course of history for a whole country, or even for the world. The inherent danger is that their obsession blinds them to everything else that matters in normal times.